By Kewal K. Jain
Applications of Biotechnology in Oncology collects key writings by means of Kewal ok. Jain at the most crucial contributions of biotechnology to melanoma examine, quite to the molecular prognosis of melanoma and drug supply in melanoma for custom-made administration of sufferers. fundamentals of varied “omics” applied sciences and their software in oncology are defined as oncogenomics and oncoproteomics. This precise quantity additionally explores molecular diagnostics, nanobiotechnology, telephone and gene cures, in addition to custom-made oncology. With nearly a thousand chosen references from contemporary literature in this subject and diverse tables and figures, Applications of Biotechnology in Oncology serves as a great reference for oncologists, scientists fascinated about examine on melanoma biology, and physicians in a variety of specialties who care for cancer.
Read Online or Download Applications of Biotechnology in Oncology PDF
Best oncology books
In March 2001, the nationwide Institutes of well-being issued the subsequent caution: "The variety of websites delivering health-related assets grows each day. Many websites supply important info, whereas others could have details that's unreliable or deceptive. " additionally, a result of quick elevate in Internet-based info, many hours could be wasted looking out, picking, and printing.
Lengthy validated as a staple reference for all radiation oncologists, Radiotherapy for Head and Neck Cancers: symptoms and strategies is now in its 3rd version. This thoroughly up-to-date variation offers the cutting-edge protocols at the moment used on the M. D. Anderson melanoma heart and carefully explains the rules, nomenclature, and medical use of intensity-modulated radiotherapy (IMRT).
''Written for ache administration Practitioners, Oncologists, Oncology Nurses, Nurse Practitioners, Social employees, Pharmacologists, and first Care Practitioners, in addition to scholars in those fields, this reference offers perception into chemotherapy-induced neuropathic ache melanoma survivors undergo. It stories the elemental and scientific learn into the traditional body structure of ache transmission pathways, neuropathic ache pathology, the chemotherapeutic drug mechanisms of motion and antagonistic results, chemotherapy-induced neuropathy, and drug discovery efforts for therapy.
- Electroporation-based therapies for cancer : from basics to clinical applications
- From melanocytes to melanoma: the progression to malignancy
- Plumer's Principles and Practice of Infusion Therapy
- Physicians' Cancer Chemotherapy Drug Manual (Jones and Bartlett Series in Oncology(physician's Cancer Che)
- Genetic Predisposition to Cancer, 2Ed
- A Practical Guide to Human Cancer Genetics
Additional info for Applications of Biotechnology in Oncology
The heterogeneity of cancer cells with respect to their sensitivity to various death stimuli further emphasizes the need for additional death pathways in the therapeutic control of cell death. An understanding of the molecular control of alternative death pathways is beginning to emerge. Drugs or drug targets engaging caspase-independent death routines already exist, and an example is topoisomerase inhibitor camptothecin, which induces cathepsin-mediated apoptosis-like programmed cell death in hepatocellular carcinoma cells.
Centrosomes are abnormal in most aggressive carcinomas, and centrosome defects have been implicated in chromosome instability and loss of cell cycle control in invasive carcinoma. A significant fraction of precursor lesions to some of the most common human cancers had centrosome defects, including in situ carcinomas of the uterine cervix, prostate, and female breast. Moreover, centrosome defects occur together with mitotic spindle defects, chromosome instability, and high cytological grade. Because most preinvasive lesions are not uniformly mutant for p53, the development of centrosome defects does not appear to require abrogation of p53 function.
Self-cannibalization, called autophagy, occurs when a cell forms a membrane around a part of its cytoplasm or an organelle and then digests the contents, leaving a cavity. A cell that dies from autophagy is riddled with cavities. Cells normally employ autophagy temporarily to survive when nutrients are short, to recycle components to form new organelles, or to fend off viral or bacterial infection. In cancer research, there is evidence both that autophagy is a form of programmed cell death triggered to prevent the replication of damaged cells and that cancer cells in some instances employ it to survive attack.
Applications of Biotechnology in Oncology by Kewal K. Jain